Expresión de búsqueda:
AGOUTI-RELATED PROTEIN
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Agouti-Related Protein
Descriptor
Español
:
Proteína Relacionada con Agouti
Descriptor
Portugués
:
Proteína Relacionada à Agouti
Categoría:
D12.644.276.074
D12.776.467.074
D23.529.074
Definición
Inglés
:
A secreted protein of approximately 131
amino acids
that is related to
AGOUTI SIGNALING PROTEIN
and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the
HYPOTHALAMUS
and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate
food
intake and
body weight
. Elevated AGRP has been associated with
OBESITY.
Nota Histórica
Inglés
:
2008 (1997)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52759
Identificador Único:
D054369
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS